Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846002 | 0.93 | ACHE (0.43) | PPARGESR2FFAR1AKR1B1ALDH1A1 | |
| SCHEMBL9310919 | 0.88 | PPARG (0.47) | PPARGESR2FFAR1AKR1B1ALDH1A1 | |
| SCHEMBL9308992 | 0.85 | CYP1A2 (0.45) | PPARGESR2FFAR1AKR1B1ALDH1A1 | |
| SCHEMBL9307715 | 0.84 | PPARG (0.49) | PPARGESR2 | |
| SCHEMBL9311025 | 0.84 | PPARG (0.49) | PPARGESR2FFAR1AKR1B1ACHE | |
| SCHEMBL9309735 | 0.84 | PPARG (0.48) | PPARGESR2FFAR1AKR1B1ACHE | |
| SCHEMBL8312740 | 0.84 | PPARG (0.48) | PPARGESR2 | |
| SCHEMBL7315508 | 0.84 | ESR2 (0.42) | PPARGESR2FFAR1AKR1B1ALDH1A1 | |
| SCHEMBL7308446 | 0.82 | PPARG (0.47) | PPARGESR2ACHE | |
| SCHEMBL7312142 | 0.81 | PPARG (0.46) | PPARGESR2FFAR1AKR1B1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |