Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846146 | 1.00 | LMNA (0.33) | LMNARPS6KA2ALDH1A1MEN1KMT2A | |
| SCHEMBL9431737 | 0.87 | NR1H3 (0.33) | LMNARPS6KA2ALDH1A1MEN1KMT2A | |
| SCHEMBL9431734 | 0.87 | NR1H3 (0.33) | LMNARPS6KA2ALDH1A1MEN1KMT2A | |
| SCHEMBL9848744 | 0.68 | MAPK1 (0.51) | LMNARPS6KA2ALDH1A1MEN1KMT2A | |
| SCHEMBL28669956 | 0.65 | DRD3 (0.41) | RPS6KA2ALDH1A1MEN1KMT2ACASP3 | |
| SCHEMBL7952503 | 0.64 | NFE2L2 (0.52) | MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL7952506 | 0.64 | NFE2L2 (0.52) | MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL6752627 | 0.63 | CYP1A2 (0.44) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6752629 | 0.63 | CYP1A2 (0.44) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19533850 | 0.62 | CASP3 (0.43) | RPS6KA2ALDH1A1MEN1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |