Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280809 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL9846179 | 0.79 | GRIN2D (0.34) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL9278617 | 0.78 | MAPT (0.34) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL9846391 | 0.78 | MAPT (0.34) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| L-697661 SCHEMBL29456987 | 0.78 | FABP4 (0.34) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| L-697661 SCHEMBL599639 | 0.78 | FABP4 (0.34) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL9846178 | 0.77 | ALDH1A1 (0.31) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL9846185 | 0.77 | ALDH1A1 (0.31) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL9846155 | 0.77 | MEN1 (0.31) | ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL9431759 | 0.76 | RAB9A (0.41) | HCAR2MAPTSMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |