Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.50 |
| ▸ | WNT3A | P56704 | 2/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13597696 | 0.81 | ALDH1A1 (0.59) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3183222 | 0.80 | ALDH1A1 (0.79) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2012414 | 0.79 | RAB9A (0.45) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3868572 | 0.78 | RAB9A (0.59) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3235289 | 0.77 | ALDH1A1 (0.74) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4285186 | 0.77 | ALDH1A1 (0.68) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12310969 | 0.77 | NPC1 (0.62) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3868570 | 0.76 | RAB9A (0.58) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4126479 | 0.76 | ALDH1A1 (0.72) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7180322 | 0.76 | ALDH1A1 (0.72) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431421-A2 | Heteroarylsubstituted pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |