Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25647559 | 0.79 | ALDH1A1 (0.42) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL27752610 | 0.76 | ALDH1A1 (0.43) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL9680298 | 0.76 | PDE4A (0.44) | MAPTALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL22222467 | 0.76 | POLB (0.42) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL9681760 | 0.74 | ALDH1A1 (0.39) | MAPTALDH1A1KDM4EL3MBTL1ACHE | |
| SCHEMBL694204 | 0.74 | NOS3 (0.41) | MAPTALDH1A1KDM4ENQO2NPC1 | |
| SCHEMBL21362701 | 0.73 | HMGCR (0.41) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL1912056 | 0.72 | ACHE (0.52) | MAPTALDH1A1KDM4EL3MBTL1NQO2 | |
| SCHEMBL2954181 | 0.72 | TAAR1 (0.56) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL14369657 | 0.71 | ALDH1A1 (0.56) | MAPTALDH1A1PRNPNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |