Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432062 | 1.00 | ELANE (0.31) | ELANEAPOBEC3AAPOBEC3G | |
| SCHEMBL9846323 | 0.84 | — | — | |
| SCHEMBL9846324 | 0.84 | — | — | |
| SCHEMBL9846156 | 0.76 | ALOX5 (0.31) | — | |
| SCHEMBL9432051 | 0.74 | APOBEC3A (0.33) | APOBEC3AAPOBEC3G | |
| SCHEMBL9846119 | 0.72 | TTR (0.30) | — | |
| SCHEMBL9846121 | 0.72 | TTR (0.30) | — | |
| SCHEMBL9267418 | 0.70 | ALDH1A1 (0.39) | APOBEC3AAPOBEC3G | |
| SCHEMBL9846194 | 0.69 | PDE3B (0.36) | — | |
| SCHEMBL9846195 | 0.69 | PDE3B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |