Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846247 | 0.78 | L3MBTL1 (0.44) | L3MBTL1MAOBATP4AATP4BSTAT3 | |
| SCHEMBL15132085 | 0.77 | MAOB (0.45) | CNR1L3MBTL1MAOBSTAT3HTT | |
| SCHEMBL9585493 | 0.76 | HTT (0.65) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL9846083 | 0.76 | HTT (0.50) | CNR1L3MBTL1SQORMAOBXDH | |
| SCHEMBL9586720 | 0.76 | ALDH1A1 (0.48) | CNR1L3MBTL1SQORMAOBXDH | |
| SCHEMBL2529051 | 0.76 | MAOB (0.48) | CNR1L3MBTL1SQORMAOBXDH | |
| SCHEMBL9846091 | 0.75 | ALDH1A1 (0.53) | CNR1XDHHTTSMN1; SMN2KDM4E | |
| SCHEMBL4286787 | 0.73 | HDAC1 (0.58) | CNR1L3MBTL1SQORMAOBXDH | |
| SCHEMBL9846090 | 0.73 | KDM4E (0.69) | L3MBTL1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2527923 | 0.73 | MAOB (0.48) | CNR1L3MBTL1SQORMAOBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |