Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585493 | 0.89 | HTT (0.65) | ALDH1A1KDM4EHPGDCRHBPCRHR2 | |
| SCHEMBL9846090 | 0.86 | KDM4E (0.69) | ALDH1A1KDM4EHPGDCRHBPCRHR2 | |
| SCHEMBL9846083 | 0.84 | HTT (0.50) | ALDH1A1KDM4EHPGDCRHBPCRHR2 | |
| SCHEMBL9846310 | 0.80 | MEN1 (0.45) | ALDH1A1KDM4ESMN1; SMN2HTTGAA | |
| SCHEMBL23120426 | 0.77 | CYP1A2 (0.51) | ALDH1A1KDM4EHPGDCRHBPCRHR2 | |
| SCHEMBL23135737 | 0.77 | CYP1A2 (0.58) | ALDH1A1KDM4EHPGDCRHBPCRHR2 | |
| SCHEMBL9586720 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDCRHBPCRHR2 | |
| SCHEMBL9846264 | 0.75 | CNR1 (0.47) | ALDH1A1KDM4EHPGDCRHBPCRHR2 | |
| SCHEMBL2624180 | 0.75 | L3MBTL1 (0.60) | KDM4EHPGDSMN1; SMN2HTTLMNA | |
| SCHEMBL16616758 | 0.74 | MCL1 (0.55) | SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |