Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.39 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846135 | 0.85 | L3MBTL1 (0.44) | MEN1HSP90AA1KMT2AL3MBTL1MCL1 | |
| SCHEMBL15088137 | 0.80 | L3MBTL1 (0.46) | MEN1HSP90AA1KMT2AL3MBTL1MCL1 | |
| SCHEMBL9338308 | 0.80 | L3MBTL1 (0.48) | MEN1HSP90AA1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9846091 | 0.80 | ALDH1A1 (0.53) | CNR1ALDH1A1GAAKDM4EHTT | |
| SCHEMBL9846147 | 0.79 | MEN1 (0.41) | MEN1HSP90AA1KMT2AL3MBTL1CNR1 | |
| SCHEMBL9846142 | 0.79 | MEN1 (0.41) | MEN1HSP90AA1KMT2AL3MBTL1CNR1 | |
| SCHEMBL9586039 | 0.78 | ALDH1A1 (0.48) | MEN1HSP90AA1KMT2AL3MBTL1MCL1 | |
| SCHEMBL15088136 | 0.78 | L3MBTL1 (0.46) | MEN1HSP90AA1KMT2AL3MBTL1CNR1 | |
| SCHEMBL9846247 | 0.76 | L3MBTL1 (0.44) | MEN1HSP90AA1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL16616758 | 0.75 | MCL1 (0.55) | MEN1HSP90AA1KMT2AL3MBTL1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |