SCHEMBL9846340

SCHEMBL9846340

C=Cc1ccc(OC)cc1.C=Cc1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.47
RELA Q04206 5/20 0.46
NFE2L2 Q16236 2/20 0.46
TUBB1 Q9H4B7 1/20 0.42
ALDH1A1 P00352 4/20 0.41
CYP2A6 P11509 1/20 0.41
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX5 P09917 1/20 0.40
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
SNCA P37840 1/20 0.40
KEAP1 Q14145 1/20 0.40
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1637292 0.82 ALDH1A1 (0.44) RELANFE2L2ALDH1A1CYP2A6TSHR
SCHEMBL15048521 0.81 RELA (0.54) TRPA1RELANFE2L2ALDH1A1CYP2A6
Styrene SCHEMBL139395 0.81 ALDH1A1 (0.61) TRPA1NFE2L2ALDH1A1TSHRTP53
Styrene SCHEMBL11794937 0.81 TRPA1 (0.69) TRPA1RELANFE2L2ALDH1A1CYP2A6
Methoxymethane SCHEMBL28672347 0.81 ALDH1A1 (0.50) ALDH1A1TSHRTP53ALOX5PTGS1
SCHEMBL678625 0.81 ALDH1A1 (0.58) TRPA1RELANFE2L2TUBB1ALDH1A1
SCHEMBL28436 0.81 ALDH1A1 (0.58) TRPA1RELANFE2L2TUBB1ALDH1A1
SCHEMBL8527619 0.80 RELA (0.49) RELANFE2L2TUBB1ALDH1A1CYP2A6
Potassium SCHEMBL30719694 0.79 ALDH1A1 (0.56) TRPA1RELANFE2L2TUBB1ALDH1A1
Potassium SCHEMBL30719700 0.79 ALDH1A1 (0.56) TRPA1RELANFE2L2TUBB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413465-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-02-20 EP disclosed
EP-0405785-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-02 EP disclosed