Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846369 | 0.75 | KMT2A (0.33) | MRGPRX4KDM4ENOTUMKMT2APKM | |
| SCHEMBL9846388 | 0.72 | KMT2A (0.38) | KDM4EKMT2APKMHTTALDH1A1 | |
| SCHEMBL9846375 | 0.68 | GCK (0.38) | MRGPRX4KDM4EALDH1A1LMNAMETAP2 | |
| SCHEMBL9846273 | 0.65 | POLB (0.36) | NOTUMKMT2APKMHTTGFER | |
| SCHEMBL9846331 | 0.63 | LMNA (0.43) | KDM4EKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10376804 | 0.62 | KMT2A (0.49) | KMT2AHTTGFERALDH1A1L3MBTL1 | |
| SCHEMBL3657194 | 0.62 | HSP90AA1 (0.41) | KMT2APKMHTTGFERNPC1 | |
| Pyrrole SCHEMBL5264669 | 0.60 | P2RX7 (0.37) | KMT2APKMHTTGFERALDH1A1 | |
| SCHEMBL28758529 | 0.60 | ALPI (0.47) | PKM | |
| SCHEMBL28109373 | 0.59 | HSP90AA1 (0.49) | KDM4EKMT2AHTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415569-A2 | Agrochemical compositions | ZENECA LIMITED (GB) | 1991-03-06 | — | — | EP | claimed |