Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19137414 | 0.85 | LMNA (0.53) | IRAK4MAPTKMT2ALMNAHTT | |
| SCHEMBL11696928 | 0.83 | KDM4E (0.67) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL11010377 | 0.81 | KDM4E (0.46) | IRAK4MEN1KMT2ALMNAHTT | |
| Ethane SCHEMBL2712758 | 0.81 | KDM4E (0.65) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL7672827 | 0.81 | IRAK4 (0.59) | IRAK4CTNNB1MAPTMEN1KMT2A | |
| SCHEMBL811872 | 0.81 | KDM4E (0.69) | IRAK4CTNNB1MAPTMEN1KMT2A | |
| SCHEMBL10865315 | 0.81 | KDM4E (0.69) | IRAK4CTNNB1MAPTMEN1KMT2A | |
| SCHEMBL9846404 | 0.80 | SLC6A3 (0.56) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL22833915 | 0.79 | CA1 (0.54) | KMT2ALMNAHTTKDM4EHSD17B10 | |
| SCHEMBL27623412 | 0.79 | TSHR (0.50) | MAPTKMT2ALMNACYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662987-B2 | Oxidation of 1-acyl alkyl compound under anhydrous condition | XENOPORT, INC. (US) | 2010-02-16 | — | — | US | claimed |
| US-20080255073-A1 | COMPOUNDS FOR SUSTAINED RELEASE OF ORALLY DELIVERED DRUGS | XONOPORT, INC. (US) | 2008-10-16 | — | — | US | claimed |
| US-20080026077-A1 | METHODS AND COMPOSITIONS OF GENE DELIVERY AGENTS FOR SYSTEMIC AND LOCAL THERAPY | HILFINGER JOHN | 2008-01-31 | — | — | US | claimed |
| WO-2007067779-A2 | METHODS AND COMPOSITIONS FOR DRUG DELIVERY ENHANCEMENT | TSRL, INC. (US) | 2007-06-14 | — | — | WO | claimed |
| WO-2003099293-A1 | PHARMACOLOGICALLY ACTIVE SALTS | DANMARKS FARMACEUTISKE UNIVERSITET (DK) | 2003-12-04 | — | — | WO | claimed |
| US-20240261139-A1 | METHODS AND COMPOSITIONS FOR IONTOPHORETIC DRUG DELIVERY TO THE EYE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-08-08 | — | — | US | disclosed |
| US-11998481-B2 | Methods and compositions for iontophoretic drug delivery to the eye | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-20210121325-A1 | METHODS AND COMPOSITIONS FOR IONTOPHORETIC DRUG DELIVERY TO THE EYE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-04-29 | — | — | US | disclosed |
| US-20180353613-A1 | ANIONIC NANOPARTICLES FOR USE IN THE DELIVERY OF ANIONIC SMALL MOLECULE DRUGS | B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD. (IL) | 2018-12-13 | — | — | US | disclosed |
| EP-3291838-A1 | ANIONIC NANOPARTICLES FOR USE IN THE DELIVERY OF ANIONIC SMALL MOLECULE DRUGS | B.G. Negev Technologies and Applications Ltd. (IL) | 2018-03-14 | — | — | EP | disclosed |
| WO-2016178224-A1 | ANIONIC NANOPARTICLES FOR USE IN THE DELIVERY OF ANIONIC SMALL MOLECULE DRUGS | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) | 2016-11-10 | — | — | WO | disclosed |
| US-8642644-B2 | Ophthamological drugs | DUKE UNIVERSITY (US) | 2014-02-04 | — | — | US | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |
| EP-0331471-B1 | HIGH MOLECULAR WEIGHT PRODRUG DERIVATIVES OF ANTIINFLAMMATORY DRUGS | Larsen, Claus Selch (DK) | 1992-12-16 | — | — | EP | disclosed |
| US-5073641-A | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS | BUNDGAARD HANS (DK) | 1991-12-17 | — | — | US | disclosed |
| EP-0331471-A1 | High molecular weight prodrug derivatives of antiinflammatory drugs | Larsen, Claus Selch (DK) | 1989-09-06 | — | — | EP | disclosed |
| EP-0278977-A1 | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS. | BUNDGAARD HANS (DK) | 1988-08-24 | — | — | EP | disclosed |
| WO-1988001615-A1 | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS | BUNDGAARD HANS (DK) | 1988-03-10 | — | — | WO | disclosed |
| US-4381307-A | Soft tertiary amine esters of bio-affecting carboxylic acids | MERCK & CO., INC. (US) | 1983-04-26 | — | — | US | disclosed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255073-A1 | COMPOUNDS FOR SUSTAINED RELEASE OF ORALLY DELIVERED DRUGS | ABCB11, ABCB1, SLC10A1 | IRAK4 3788/4885CTNNB1 4723/4885MAPT 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.