Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 3/20 | 0.32 |
| ▸ | KDM4B | O94953 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 5/20 | 0.31 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8992387 | 0.98 | HTR2A (0.33) | LMNAKDM4AKDM4BKDM4CMAOB | |
| Hydrochloric Acid SCHEMBL8992457 | 0.98 | HTR2A (0.33) | LMNAKDM4AKDM4BKDM4CMAOB | |
| Hydrochloric Acid SCHEMBL8992462 | 0.76 | MGAM (0.35) | MAOBALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL9587286 | 0.67 | OPRM1 (0.42) | MAOBMAOAALDH1A1HTR2AHTR2C | |
| SCHEMBL9586402 | 0.64 | ALDH1A1 (0.37) | LMNAMAOBALDH1A1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL8992428 | 0.64 | SLC6A2 (0.39) | ALDH1A1HTR2CMAPK1 | |
| SCHEMBL8992294 | 0.63 | ALDH1A1 (0.37) | LMNAMAOBMAOAALDH1A1KCNH2 | |
| SCHEMBL8992309 | 0.63 | ALDH1A1 (0.37) | LMNAMAOBMAOAALDH1A1KCNH2 | |
| SCHEMBL8992275 | 0.62 | MAOB (0.32) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL8992298 | 0.62 | OPRM1 (0.41) | MAOBMAOAALDH1A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |