Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553669 | 0.88 | ERN1 (0.41) | ERN1ALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL9846472 | 0.81 | ERN1 (0.36) | ERN1THRBALDH1A1POLBRAB9A | |
| SCHEMBL8125146 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL11025473 | 0.77 | ALDH1A1 (0.40) | THRBALDH1A1POLBHTTTDP1 | |
| SCHEMBL11023135 | 0.77 | ALDH1A1 (0.47) | THRBALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL11027638 | 0.76 | THRB (0.42) | THRBALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL11026162 | 0.74 | ALDH1A1 (0.56) | THRBALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL11027009 | 0.74 | KMT2A (0.42) | THRBALDH1A1POLBHTTTDP1 | |
| SCHEMBL9706985 | 0.73 | ALDH1A1 (0.37) | ALDH1A1POLBRAB9ASMN1; SMN2HTT | |
| SCHEMBL11028007 | 0.73 | THRB (0.42) | THRBALDH1A1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411157-A1 | SPIROPYRAN COMPOUNDS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1991-02-06 | — | — | EP | disclosed |