Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674692 | 0.72 | MAOB (0.33) | MAPTKMT2ARAB9AMEN1GAA | |
| SCHEMBL9772859 | 0.72 | GAA (0.37) | MAPTKMT2ARAB9APOLBGPR55 | |
| SCHEMBL9846576 | 0.72 | EGFR (0.32) | MAPTRAB9AGAARENAPP | |
| SCHEMBL4394813 | 0.70 | SLC6A2 (0.34) | KMT2AMEN1POLBGAABACE1 | |
| SCHEMBL11469864 | 0.64 | CFTR (0.39) | MMP2MMP9MAPTKMT2ARAB9A | |
| SCHEMBL6827479 | 0.64 | BACE1 (0.43) | MMP2MMP9KMT2ARENAPP | |
| SCHEMBL7662936 | 0.63 | MMP2 (0.37) | MMP2MMP9KMT2APOLBGPR55 | |
| SCHEMBL28548234 | 0.63 | HCAR2 (0.53) | MMP2MMP9CFTRGOPCCYP1A2 | |
| SCHEMBL4397735 | 0.63 | CFTR (0.34) | MMP2MMP9MAPTKMT2ARAB9A | |
| SCHEMBL7635908 | 0.61 | CFTR (0.56) | MMP2MMP9MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455909-A2 | 5-[1-(Imidazol)methyl]-3,3-disubstituted-2(3H) furanone derivatives | MARION MERRELL DOW INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| US-5039691-A | Anticholinergic agents | MARION MERRELL DOW INC. (US) | 1991-08-13 | — | — | US | disclosed |