Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846715 | 0.86 | CTSD (0.36) | BACE1CTSDMEN1KMT2ATSHR | |
| SCHEMBL9372531 | 0.83 | ABCC9 (0.47) | BACE1CTSDMALT1ABCC9ABCC8 | |
| SCHEMBL9372884 | 0.83 | CASP6 (0.39) | MALT1MEN1KMT2APOLB | |
| SCHEMBL9846780 | 0.83 | PDK2 (0.39) | MEN1KMT2ATSHRHSD11B1HDAC8 | |
| SCHEMBL9372313 | 0.80 | CASP6 (0.39) | MALT1MEN1KMT2APOLB | |
| SCHEMBL9375925 | 0.80 | ABCC9 (0.44) | BACE1CTSDMALT1ABCC9ABCC8 | |
| SCHEMBL9846720 | 0.79 | PBRM1 (0.37) | BACE1CTSDMALT1PBRM1 | |
| SCHEMBL9733185 | 0.74 | SMN1; SMN2 (0.33) | BACE1CTSDMALT1HSD17B10MEN1 | |
| SCHEMBL9737580 | 0.73 | SMN1; SMN2 (0.35) | MALT1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL9372070 | 0.72 | BACE1 (0.33) | BACE1CTSDMALT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |