Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733242 | 0.84 | ALDH1A1 (0.39) | SMN1; SMN2TSHRKMT2AMEN1LMNA | |
| SCHEMBL9733898 | 0.84 | ABCC9 (0.45) | SMN1; SMN2TSHRLMNAPOLBMALT1 | |
| SCHEMBL9733223 | 0.84 | MEN1 (0.38) | KMT2AMEN1KDM4EHTTRAB9A | |
| SCHEMBL9733029 | 0.81 | ALDH1A1 (0.38) | SMN1; SMN2TSHRKMT2AMEN1LMNA | |
| SCHEMBL9737580 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHRKMT2AMEN1LMNA | |
| SCHEMBL9665033 | 0.76 | NPC1 (0.35) | SMN1; SMN2TSHRKMT2AMEN1LMNA | |
| SCHEMBL9737951 | 0.74 | PTGER1 (0.34) | SMN1; SMN2TSHRKMT2AKDM4EPOLB | |
| SCHEMBL9733388 | 0.74 | NR1H4 (0.32) | KMT2AMEN1HTTRAB9A | |
| SCHEMBL9846729 | 0.74 | BACE1 (0.37) | TSHRKMT2AMEN1POLBIDO1 | |
| SCHEMBL9664156 | 0.70 | HDAC3 (0.34) | SMN1; SMN2TSHRKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |