Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27572151 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL27496366 | 0.85 | TSHR (0.41) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL4432272 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL30301191 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL1980955 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL4990894 | 0.79 | TSHR (0.46) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL1977826 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL1980412 | 0.77 | TSHR (0.48) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL28006286 | 0.76 | ENPP2 (0.44) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 | |
| SCHEMBL1980600 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1TDP1ENPP2LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408990-A2 | Thermosetting reaction resin mixture | SIEMENS AKTIENGESELLSCHAFT (DE) | 1991-01-23 | — | — | EP | disclosed |