Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 2/20 | 0.41 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846708 | 0.87 | AGTR1 (0.54) | AGTR1AGTR2HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL9846728 | 0.78 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9846722 | 0.72 | AGTR1 (0.52) | AGTR1AGTR2HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL9846687 | 0.71 | AGTR1 (0.51) | AGTR1AGTR2HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL10576800 | 0.71 | AGTR1 (0.60) | AGTR1AGTR2HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL9846795 | 0.70 | AGTR1 (0.48) | AGTR1AGTR2HSP90AA1 | |
| SCHEMBL9309540 | 0.69 | AGTR1 (0.54) | AGTR1AGTR2HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL8734933 | 0.69 | KDM4E (0.57) | — | |
| SCHEMBL9846714 | 0.68 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9309546 | 0.68 | AGTR1 (0.54) | AGTR1AGTR2HSP90AA1HSP90B1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |