Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431348 | 0.91 | KIF11 (0.46) | KIF11ARMERTKKMT2AMRGPRX4 | |
| SCHEMBL11039112 | 0.90 | KIF11 (0.47) | KIF11ARKMT2AKDM4ELMNA | |
| SCHEMBL4493473 | 0.81 | TLR7 (0.39) | TLR7NPBWR1MCHR1TLR8 | |
| SCHEMBL4493478 | 0.81 | NPBWR1 (0.46) | ARKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL3104195 | 0.81 | TLR7 (0.39) | TLR7NPBWR1MCHR1TLR8L3MBTL1 | |
| SCHEMBL9582221 | 0.81 | MAOB (0.41) | KIF11KMT2ATLR7NPBWR1MCHR1 | |
| SCHEMBL9048157 | 0.81 | AR (0.33) | ARMRGPRX4TLR7NPBWR1MCHR1 | |
| SCHEMBL9847110 | 0.81 | AR (0.43) | AR | |
| SCHEMBL921021 | 0.77 | FFAR1 (0.54) | KIF11ARMERTKKMT2AMRGPRX4 | |
| SCHEMBL9711446 | 0.77 | TRPV4 (0.35) | ARMRGPRX4SCN9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034402-B1 | METHOD OF PREPARING FLUORINE-SUBSTITUTED DIPHENYL ETHER DERIVATIVES AND FLUORINE-SUBSTITUTED HALOGENO BENZENE DERIVATIVES FOR USE THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-29 | — | — | EP | disclosed |
| US-4384135-A | REACTING A SUBSTITUTED BENZOTRIFLUORIDE WITH A SUBSTITUTED PHENOL | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-17 | — | — | US | disclosed |
| EP-0034402-A2 | Method of preparing fluorine-substituted diphenyl ether derivatives and fluorine-substituted halogeno benzene derivatives for use therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-26 | — | — | EP | disclosed |