SCHEMBL9847558

SCHEMBL9847558

COC1(C)CCc2ccc(Oc3ccc(N=C=O)cc3)cc2O1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.38
PPARG P37231 18/20 0.38
PPARD Q03181 2/20 0.36
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847583 0.89 PPARA (0.40) PPARAPPARGPPARD
SCHEMBL9847532 0.88 PPARA (0.36) PPARAPPARGPPARD
SCHEMBL9749254 0.87 PPARG (0.39) PPARAPPARGPPARD
SCHEMBL9847571 0.84 PPARG (0.42) PPARAPPARGPPARD
SCHEMBL9754845 0.82 RXRA (0.33)
SCHEMBL9847588 0.81 ALDH1A1 (0.44) PPARAPPARGPPARD
SCHEMBL9847591 0.78 HIF1A (0.33)
SCHEMBL9847566 0.78
SCHEMBL9749319 0.78 DAGLA (0.47) PPARAPPARG
SCHEMBL9847575 0.75 PPARG (0.40) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed