SCHEMBL9847591

SCHEMBL9847591

COC1(C)Oc2cc(Oc3ccc(N=C=O)cc3)ccc2CC1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.33
BACE1 P56817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847582 0.82 ALDH1A1 (0.43) HIF1A
SCHEMBL9847558 0.78 PPARA (0.38)
SCHEMBL9749254 0.76 PPARG (0.39)
SCHEMBL9847646 0.76 HIF1A (0.37) HIF1A
SCHEMBL9847597 0.74 MEN1 (0.41) HIF1A
SCHEMBL9847566 0.74
SCHEMBL9754845 0.73 RXRA (0.33)
SCHEMBL9847571 0.73 PPARG (0.42)
SCHEMBL9847583 0.72 PPARA (0.40)
SCHEMBL9847532 0.71 PPARA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed