SCHEMBL9847583

SCHEMBL9847583

CCOC1(C)CCc2ccc(Oc3ccc(N=C=O)cc3)cc2O1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.40
PPARG P37231 18/20 0.40
PPARD Q03181 2/20 0.37
ABHD6 Q9BV23 1/20 0.33
DAGLA Q9Y4D2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847558 0.89 PPARA (0.38) PPARAPPARGPPARD
SCHEMBL9847532 0.86 PPARA (0.36) PPARAPPARGPPARD
SCHEMBL9749254 0.85 PPARG (0.39) PPARAPPARGPPARDABHD6DAGLA
SCHEMBL9847605 0.83 ALDH1A1 (0.42) PPARAPPARGPPARD
SCHEMBL9847530 0.83 CYP3A4 (0.33)
SCHEMBL9847571 0.82 PPARG (0.42) PPARAPPARGPPARD
SCHEMBL9847547 0.77 PPARA (0.42) PPARAPPARGPPARD
SCHEMBL9749319 0.76 DAGLA (0.47) PPARAPPARGABHD6DAGLA
SCHEMBL9847645 0.75 PPARA (0.40) PPARAPPARGPPARD
SCHEMBL9847603 0.74 RXRA (0.31) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed