Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501158 | 0.82 | KDM4E (0.42) | CYP11B1CYP11B2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL31362449 | 0.81 | S1PR4 (0.58) | LMNARAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL3665962 | 0.81 | RAB9A (0.55) | LMNARAB9ASMN1; SMN2MEN1NPC1 | |
| Ammonia Solution, Strong SCHEMBL28511290 | 0.81 | CHRNB2 (0.47) | LMNARAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL2974587 | 0.78 | MAPT (0.56) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL21730396 | 0.78 | KDM1A (0.40) | LMNARAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL1101341 | 0.78 | MAPT (0.69) | LMNARAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL12754892 | 0.77 | TSHR (0.45) | LMNARAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL5999885 | 0.77 | PDE5A (0.51) | CYP11B1CYP11B2LMNAMEN1KMT2A | |
| SCHEMBL23774789 | 0.77 | LMNA (0.38) | LMNARAB9ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411935-A2 | Copper radio sensitizers | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1991-02-06 | — | — | EP | disclosed |