Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | USP1 | O94782 | 3/20 | 0.31 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971527 | 0.91 | AGTR1 (0.37) | MEN1KMT2AHTR6USP1AGTR1 | |
| Ammonia Solution, Strong SCHEMBL9847783 | 0.85 | AGTR1 (0.43) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL8972510 | 0.83 | AGTR1 (0.37) | MEN1KMT2AUSP1AGTR1AGTR2 | |
| SCHEMBL9311939 | 0.82 | TLR7 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8971906 | 0.80 | PDE10A (0.41) | MEN1KMT2AHTR6AGTR1AGTR2 | |
| SCHEMBL8971629 | 0.79 | AGTR1 (0.41) | MEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL8565215 | 0.77 | AGTR1 (0.37) | MEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL8972563 | 0.76 | AGTR1 (0.53) | MEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL9872558 | 0.76 | HTR6 (0.32) | HTR6 | |
| SCHEMBL9053246 | 0.76 | AGTR1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |