Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847804 | 0.93 | AGTR1 (0.58) | AGTR2AGTR1PPARG | |
| SCHEMBL9847839 | 0.91 | PPARG (0.58) | AGTR2AGTR1PPARG | |
| SCHEMBL8972327 | 0.89 | AGTR1 (0.73) | AGTR2AGTR1PPARG | |
| SCHEMBL9847850 | 0.86 | AGTR1 (0.59) | AGTR2AGTR1PPARG | |
| SCHEMBL9847864 | 0.85 | AGTR1 (0.58) | AGTR2AGTR1PPARG | |
| SCHEMBL9847874 | 0.85 | AGTR1 (0.55) | AGTR2AGTR1PPARG | |
| SCHEMBL8958505 | 0.85 | AGTR1 (0.81) | AGTR2AGTR1PPARG | |
| SCHEMBL9847799 | 0.84 | AGTR1 (0.56) | AGTR2AGTR1PPARG | |
| SCHEMBL8972109 | 0.82 | AGTR1 (0.72) | AGTR2AGTR1PPARG | |
| SCHEMBL9847884 | 0.81 | AGTR2 (0.50) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |