SCHEMBL9848239

SCHEMBL9848239

CCCCCCCCCCCCS(=O)(=O)Nc1cccc(C(N)=O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MAP1LC3B Q9GZQ8 1/20 0.48
MAP1LC3A Q9H492 1/20 0.48
ATIC P31939 1/20 0.46
PARP1 P09874 3/20 0.46
PARP10 Q53GL7 3/20 0.46
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
PARP14 Q460N5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27846668 0.88 WDR5 (0.53)
SCHEMBL11396218 0.88 ALDH1A1 (0.58) THRAMAP1LC3BMAP1LC3A
SCHEMBL9848235 0.87 THRA (0.48) THRAMAP1LC3BMAP1LC3AAURKAKDR
SCHEMBL28043234 0.86 THRA (0.54) THRAMAP1LC3BMAP1LC3AAURKAKDR
SCHEMBL11402532 0.85 THRA (0.49) THRAMAP1LC3BMAP1LC3AAURKAKDR
SCHEMBL10965567 0.82 WDR5 (0.55) MAP1LC3BMAP1LC3AAURKAKDRAURKB
SCHEMBL4496533 0.81 MAP1LC3B (0.52) THRAMAP1LC3BMAP1LC3AAURKAKDR
SCHEMBL6295432 0.81 MAP1LC3B (0.48) THRAMEN1KMT2AMAP1LC3BMAP1LC3A
SCHEMBL8756642 0.81 MAP1LC3B (0.48) THRAMEN1KMT2AMAP1LC3BMAP1LC3A
SCHEMBL10884996 0.81 MAP1LC3B (0.48) THRAMEN1KMT2AMAP1LC3BMAP1LC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0421453-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-10 EP disclosed