SCHEMBL9848293

SCHEMBL9848293

Cc1cc(N)cc(Nc2c(C)cc(C)cc2C)c1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 19/20 0.79
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6711280 0.79 RAPGEF4 (0.73) RAPGEF4
SCHEMBL19087412 0.74 RAPGEF4 (0.71) RAPGEF4ALDH1A1
SCHEMBL502929 0.74 RAPGEF4 (1.00) RAPGEF4
SCHEMBL12991010 0.73 ALDH1A1 (0.60) RAPGEF4ALDH1A1TSHR
SCHEMBL15174034 0.72 RAPGEF4 (1.00) RAPGEF4
SCHEMBL9387093 0.72 RAPGEF4 (0.68) RAPGEF4
SCHEMBL9848295 0.72 NPSR1 (0.62) RAPGEF4ALDH1A1TSHR
SCHEMBL15188815 0.71 RAPGEF4 (1.00) RAPGEF4
SCHEMBL4909608 0.71 TOP2A (0.64)
SCHEMBL1323030 0.71 RAPGEF4 (0.65) RAPGEF4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413338-A1 Electrophotosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1991-02-20 EP disclosed