Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848308 | 0.86 | CA12 (0.42) | MAOBMAOA | |
| SCHEMBL5480380 | 0.77 | OPRM1 (0.41) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL28381060 | 0.73 | MAOB (0.44) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL3685814 | 0.72 | ALOX15 (0.42) | — | |
| SCHEMBL9848309 | 0.72 | MAOB (0.46) | MAOBMAOA | |
| SCHEMBL9848306 | 0.72 | MAOB (0.39) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL3684089 | 0.72 | ALOX15 (0.42) | — | |
| Perfluorocyclobutane SCHEMBL19582011 | 0.71 | ALDH1A1 (0.64) | MAOA | |
| SCHEMBL9848312 | 0.71 | CYP3A4 (0.46) | MAOBMAOA | |
| SCHEMBL9848315 | 0.67 | TP53 (0.39) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438715-A2 | 1,1-Bicyclo-substituted fluorinated cyclopentanes and method for their production | BAYER AG (DE) | 1991-07-31 | — | — | EP | disclosed |