Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848301 | 0.75 | CYP2A6 (0.38) | OPRM1OPRK1OPRL1TSHR | |
| SCHEMBL9848313 | 0.75 | MAOB (0.43) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL31134789 | 0.75 | OPRM1 (0.37) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL9848304 | 0.72 | MAOB (0.42) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| Perfluorocyclobutane SCHEMBL19582011 | 0.67 | ALDH1A1 (0.64) | MAOA | |
| SCHEMBL9848308 | 0.67 | CA12 (0.42) | MAOBMAOA | |
| SCHEMBL13563561 | 0.67 | MAOB (0.45) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL11749210 | 0.63 | POLB (0.43) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL28593200 | 0.62 | MAOB (0.43) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL1464628 | 0.61 | MAOB (0.42) | MAOBMAOAOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438715-A2 | 1,1-Bicyclo-substituted fluorinated cyclopentanes and method for their production | BAYER AG (DE) | 1991-07-31 | — | — | EP | disclosed |