SCHEMBL9848321

SCHEMBL9848321

O=c1ccnc(NC2O[C@H](C(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)[nH]1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16008962 0.74 RAB9A (0.38) SMN1; SMN2
SCHEMBL16098965 0.74 RAB9A (0.38) SMN1; SMN2
SCHEMBL2287366 0.71 HPRT1 (0.32)
SCHEMBL2292031 0.70
SCHEMBL11875859 0.67
SCHEMBL8042880 0.67
SCHEMBL11211804 0.62 ITPR3 (0.33)
Water SCHEMBL6021925 0.61 ADORA1 (0.33) KMT2ASMN1; SMN2
SCHEMBL11130784 0.61 SMN1; SMN2 (0.51) SMN1; SMN2
SCHEMBL11123373 0.60 IMPDH2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0405370-A1 Riboflavinoverproducing strains of bacteria F. HOFFMANN-LA ROCHE AG (CH) 1991-01-02 EP disclosed