Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525664 | 0.84 | FAAH (0.49) | ALDH1A1MAPTFAAHACE2 | |
| SCHEMBL22689608 | 0.83 | TDP1 (0.45) | PTPN1ALDH1A1USP2CYP3A4MAPT | |
| SCHEMBL17466185 | 0.82 | ALDH1A1 (0.47) | PTPN1ALDH1A1USP2CYP3A4MAPT | |
| SCHEMBL28323464 | 0.82 | ACE2 (0.52) | ALDH1A1MAPTFAAHACE2 | |
| SCHEMBL27761768 | 0.82 | ACE2 (0.52) | ALDH1A1MAPTFAAHACE2 | |
| SCHEMBL4585164 | 0.82 | ACE2 (0.52) | ALDH1A1MAPTFAAHACE2 | |
| SCHEMBL16556659 | 0.82 | ACE2 (0.52) | ALDH1A1MAPTFAAHACE2 | |
| SCHEMBL27257661 | 0.82 | ACE2 (0.52) | ALDH1A1MAPTFAAHACE2 | |
| SCHEMBL19302152 | 0.82 | PTPN1 (0.40) | PTPN1ALDH1A1USP2CYP3A4MAPT | |
| SCHEMBL11821362 | 0.82 | ALDH1A1 (0.50) | PTPN1ALDH1A1CYP3A4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |