Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 3/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.48 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679385 | 0.73 | KMT2A (0.55) | SOAT2SOAT1ACAT1ALDH1A1KMT2A | |
| SCHEMBL9679723 | 0.73 | SOAT2 (0.57) | SOAT2SOAT1KMT2A | |
| SCHEMBL6335726 | 0.73 | SOAT2 (0.57) | SOAT2SOAT1KMT2A | |
| SCHEMBL9504026 | 0.73 | SOAT2 (0.57) | SOAT2SOAT1 | |
| SCHEMBL6335727 | 0.73 | SOAT2 (0.57) | SOAT2SOAT1KMT2A | |
| SCHEMBL855984 | 0.71 | SOAT2 (0.47) | SOAT2SOAT1ACAT1KMT2A | |
| SCHEMBL9848428 | 0.71 | SOAT2 (0.50) | SOAT2SOAT1ACAT1 | |
| SCHEMBL9848492 | 0.70 | SOAT2 (0.49) | SOAT2SOAT1 | |
| SCHEMBL9723446 | 0.70 | SOAT1 (0.53) | SOAT2SOAT1KMT2A | |
| SCHEMBL9735667 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | claimed |
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |