Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.50 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855763 | 0.74 | GAA (0.50) | — | |
| SCHEMBL9513684 | 0.73 | EPHX1 (0.63) | SOAT2SOAT1 | |
| SCHEMBL9513440 | 0.73 | MTNR1A (0.64) | — | |
| SCHEMBL9514663 | 0.71 | CES2 (0.62) | TRPV1 | |
| SCHEMBL9679385 | 0.71 | KMT2A (0.55) | SOAT2ACAT1SOAT1 | |
| SCHEMBL9848424 | 0.71 | SOAT2 (0.48) | SOAT2ACAT1SOAT1 | |
| SCHEMBL9514688 | 0.69 | KDM4E (0.61) | CNR1 | |
| SCHEMBL9680238 | 0.68 | SOAT2 (0.52) | SOAT2SOAT1 | |
| SCHEMBL9192380 | 0.68 | SOAT1 (0.69) | SOAT2ACAT1SOAT1 | |
| SCHEMBL9558623 | 0.68 | LPAR1 (0.55) | LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | claimed |
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |