SCHEMBL9848545

SCHEMBL9848545

O=S(=O)(c1ccccc1)c1ccc(O)c2c1CCCC2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
GFER P55789 1/20 0.51
HTR6 P50406 5/20 0.42
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PABPC1 P11940 1/20 0.40
ATM Q13315 1/20 0.40
ERAP1 Q9NZ08 1/20 0.40
HSD11B1 P28845 1/20 0.39
HSD17B2 P37059 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
BCL2L1 Q07817 1/20 0.38
BAD Q92934 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
METAP2 P50579 1/20 0.37
ABCC9 O60706 1/20 0.36
ABCC8 Q09428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10911225 0.97 POLB (0.51) POLBGAAGFERHTR6KMT2A
SCHEMBL1346827 0.73 POLB (0.59) POLBGAAGFERHTR6KMT2A
SCHEMBL10693393 0.72 LDHA (0.63) POLBGAAGFERHTR6L3MBTL1
SCHEMBL1706536 0.71 METAP2 (0.44) POLBGAAGFERHTR6KMT2A
SCHEMBL2624111 0.71 HTR6 (0.42) HTR6NPSR1HTTL3MBTL1
SCHEMBL10909931 0.71 GAA (0.42) POLBGAAGFERHTR6ATM
SCHEMBL3283307 0.71 BCL2L1 (0.56) GAAKMT2AMEN1HSD11B1HSD17B2
SCHEMBL312517 0.70 POLB (0.66) POLBGAAGFERHTR6KMT2A
SCHEMBL29709995 0.70 POLB (0.66) POLBGAAGFERHTR6KMT2A
SCHEMBL10909934 0.70 GAA (0.41) POLBGAAGFERHTR6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0405363-A2 Heat-sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1991-01-02 EP disclosed
EP-0183275-A2 Hydroxydiphenyl sulfone derivative and heat-sensitive recording material using the derivative KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1986-06-04 EP disclosed