Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8751953 | 0.96 | ACACB (0.48) | FPR2ITGA4ITGB7ABCB1HDAC8 | |
| SCHEMBL8751950 | 0.96 | ACACB (0.48) | FPR2ITGA4ITGB7ABCB1HDAC8 | |
| SCHEMBL30872672 | 0.85 | FPR2 (0.62) | FPR2HDAC8KMT2APPARGPPARA | |
| SCHEMBL29228692 | 0.85 | FPR2 (0.62) | FPR2HDAC8KMT2APPARGPPARA | |
| SCHEMBL73955 | 0.83 | MME (0.56) | MMEALDH1A1 | |
| SCHEMBL497336 | 0.83 | MME (0.56) | MMEALDH1A1 | |
| SCHEMBL11581853 | 0.83 | MME (0.56) | MMEALDH1A1 | |
| SCHEMBL27711461 | 0.82 | MEN1 (0.55) | ITGA4ITGB7KMT2AACEPPARG | |
| SCHEMBL13660693 | 0.82 | ACACB (0.50) | FPR2ABCB1KMT2AACEMME | |
| SCHEMBL31037192 | 0.82 | ACACB (0.50) | FPR2ABCB1KMT2AACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |