SCHEMBL497336

SCHEMBL497336

O=C(O)C(Cc1ccccc1)NCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.56
ALDH1A1 P00352 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54
MEP1B Q16820 2/20 0.54
PSMB5 P28074 1/20 0.54
CYP1A2 P05177 1/20 0.53
SIGMAR1 Q99720 1/20 0.53
NAALAD2 Q9Y3Q0 2/20 0.53
FOLH1 Q04609 1/20 0.51
ANPEP P15144 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11581853 1.00 MME (0.56) MMEALDH1A1NPSR1MEP1BPSMB5
SCHEMBL73955 1.00 MME (0.56) MMEALDH1A1NPSR1MEP1BPSMB5
Hydrochloric Acid SCHEMBL1027766 0.98 MME (0.54) MMEALDH1A1NPSR1MEP1BPSMB5
Hydrochloric Acid SCHEMBL7362927 0.98 MME (0.54) MMEALDH1A1NPSR1MEP1BPSMB5
SCHEMBL17915462 0.93 MME (0.61) MMEALDH1A1MMP2MMP9
SCHEMBL121370 0.92 MME (0.58) MMEALDH1A1PSMB5NAALAD2FOLH1
SCHEMBL121371 0.92 MME (0.58) MMEALDH1A1PSMB5NAALAD2FOLH1
Benzophenone SCHEMBL9490253 0.92 MEP1B (0.55) MMEALDH1A1NPSR1MEP1BPSMB5
SCHEMBL11346818 0.92 MME (0.58) MMEALDH1A1PSMB5NAALAD2FOLH1
Benzophenone SCHEMBL9490249 0.92 MEP1B (0.55) MMEALDH1A1NPSR1MEP1BPSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 639 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 CN claimed
EP-1144384-B1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARM INC (US) 2007-10-31 EP claimed
US-12594342-B2 Method of conjugation of Cys-mAbs AMGEN INC. (US) 2026-04-07 US disclosed
US-20260077054-A1 COMBINATIONS OF ANTI-GIP ANTIBODIES AND INCRETINS AND USES THEREOF HELICORE BIOPHARMA INC (US) 2026-03-19 US disclosed
US-20260034235-A1 METHOD OF CONJUGATION OF CYS-MABS AMGEN INC. (US) 2026-02-05 US disclosed
US-20260001956-A1 METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GLP-1 AGONISTS AMGEN INC. (US) 2026-01-01 US disclosed
US-20250376529-A1 METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GLP-1 AGONISTS AMGEN INC. (US) 2025-12-11 US disclosed
US-12465652-B2 Method of treating or ameliorating metabolic disorders using antagonistic binding proteins for gastric inhibitory peptide receptor (GIPR)/GLP-1 receptor agonist fusion proteins AMGEN INC. (US) 2025-11-11 US disclosed
US-20250319196-A1 METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING ANTAGONISTIC BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR)/GLP-1 RECEPTOR AGONIST FUSION PROTEINS AMGEN INC. (US) 2025-10-16 US disclosed
US-12435149-B2 Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (GIPR) in combination with GLP-1 agonists AMGEN INC. (US) 2025-10-07 US disclosed
EP-4615875-A1 METHODS FOR TREATING OBESITY AMGEN INC. (US) 2025-09-17 EP disclosed
WO-1996025394-A1 Nα-2-(4-NITROPHENULSULFONYL)ETHOXYCARBONYL-AMINO ACIDS HYUNDAI PHARM. IND. CO., LTD. (KR) 1996-08-22 WO disclosed
WO-1996023801-A2 NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME GILEAD SCIENCES, INC. (US) 1996-08-08 WO disclosed
EP-0719274-A1 METHOD FOR DOSING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 1996-07-03 EP disclosed
EP-0719273-A1 NUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1996-07-03 EP disclosed
WO-1995007919-A1 METHOD FOR DOSING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 1995-03-23 WO disclosed
WO-1995007920-A1 NUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1995-03-23 WO disclosed
EP-0107860-B1 PEPTIDES, PROCESS FOR PREPARING THE SAME AND PSYCHODEPRESSANT COMPOSITIONS CONTAINING THE SAME AMANO PHARMACEUTICAL CO., LTD. (JP) 1986-09-17 EP disclosed
EP-0107860-A1 Peptides, process for preparing the same and psychodepressant compositions containing the same AMANO PHARMACEUTICAL CO., LTD. (JP) 1984-05-09 EP disclosed
US-4069385-A FROM AN OLEFIN AND AN ORGANIC PEROXIDE WITH COPPER-SCHIFF BASE COMPEX AS CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594342-B2 Method of conjugation of Cys-mAbs TST, PTMS, TMT1A MME 4274/4885ALDH1A1 2691/4885NPSR1 3287/4885
US-20260034235-A1 METHOD OF CONJUGATION OF CYS-MABS CBS, GCLC, PTMS MME 2491/4885ALDH1A1 3399/4885NPSR1 2657/4885
US-20260001956-A1 METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GLP-1 AGONISTS GIPR, GLP1R, IAPP MME 1609/4885ALDH1A1 4129/4885NPSR1 470/4885
US-20260077054-A1 COMBINATIONS OF ANTI-GIP ANTIBODIES AND INCRETINS AND USES THEREOF GIPR, GLP1R, GPR119 MME 1884/4885ALDH1A1 4411/4885NPSR1 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.