Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8751953 | 1.00 | ACACB (0.48) | ACACBITGB3ITGA2BABCB1PPARG | |
| SCHEMBL9848618 | 0.96 | FPR2 (0.49) | ACACBITGB3ITGA2BABCB1PPARG | |
| SCHEMBL28613611 | 0.85 | ITGB3 (0.50) | ACACBITGB3ITGA2BABCB1PPARG | |
| SCHEMBL31037192 | 0.85 | ACACB (0.50) | ACACBITGB3ITGA2BABCB1PPARG | |
| SCHEMBL13660693 | 0.85 | ACACB (0.50) | ACACBITGB3ITGA2BABCB1PPARG | |
| SCHEMBL2034306 | 0.85 | ACACB (0.50) | ACACBITGB3ITGA2BABCB1PPARG | |
| SCHEMBL1097490 | 0.84 | LDHA (0.63) | PPARGPPARAFPR2LDHAHDAC8 | |
| SCHEMBL29401256 | 0.83 | ACACB (0.61) | ACACBITGB3ITGA2BABCB1PPARG | |
| SCHEMBL29398348 | 0.83 | ACACB (0.61) | ACACBITGB3ITGA2BABCB1PPARG | |
| SCHEMBL27569376 | 0.82 | ITGB3 (0.56) | ACACBITGB3ITGA2BABCB1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765307-A1 | N ALPHA-2-(4-NITROPHENULSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1997-04-02 | — | — | EP | disclosed |
| WO-1996025394-A1 | Nα-2-(4-NITROPHENULSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1996-08-22 | — | — | WO | disclosed |