Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848836 | 0.88 | CTSL (0.58) | CTSKTACR1CTRB1CTSLCTSS | |
| SCHEMBL295865 | 0.85 | PPARA (0.57) | CTSKTACR1CTRB1CTSLCTSS | |
| SCHEMBL2677964 | 0.85 | CTSK (0.57) | CTSKTACR1CTRB1CTSLCTSS | |
| SCHEMBL457686 | 0.85 | PPARA (0.57) | CTSKTACR1CTRB1CTSLCTSS | |
| SCHEMBL201710 | 0.85 | PPARA (0.57) | CTSKTACR1CTRB1CTSLCTSS | |
| SCHEMBL17446717 | 0.85 | CTSK (0.57) | CTSKTACR1CTRB1CTSLCTSS | |
| SCHEMBL7032185 | 0.85 | CTSK (0.57) | CTSKTACR1CTRB1CTSLCTSS | |
| SCHEMBL6984358 | 0.85 | CTSK (0.69) | CTSKCTSLCTSSCTSB | |
| SCHEMBL10028352 | 0.84 | ALDH1A1 (0.64) | CTSKTACR1CTRB1CTSLCTSS | |
| SCHEMBL13503284 | 0.84 | ALDH1A1 (0.64) | CTSKTACR1CTRB1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |