SCHEMBL9848995

SCHEMBL9848995

O=C(NCl)c1cccc(C(=O)c2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.69
ATM Q13315 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
ALDH1A1 P00352 2/20 0.54
PBRM1 Q86U86 1/20 0.53
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SRD5A2 P31213 1/20 0.47
CTSL P07711 1/20 0.46
MAPT P10636 2/20 0.46
PTGS1 P23219 2/20 0.46
CXCR1 P25024 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11875152 0.88 HDAC6 (0.52) L3MBTL1ALDH1A1HDAC8HDAC1HDAC2
SCHEMBL9849004 0.86 RAB9A (0.62) L3MBTL1ATMTDP1ALDH1A1CA1
SCHEMBL27515710 0.84 PKM (0.58) L3MBTL1CA1CA2HDAC8HDAC1
SCHEMBL9324919 0.83 ATM (1.00) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL135162 0.83 ATM (1.00) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL14880296 0.82 ATM (0.72) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL809769 0.81 ALOX15 (0.61) ATMTDP1ALDH1A1CA1HDAC8
SCHEMBL134300 0.81 ATM (0.95) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL134024 0.81 ATM (0.95) L3MBTL1ATMTDP1ALDH1A1PBRM1
Hydrochloric Acid SCHEMBL27790926 0.79 ALOX15 (0.58) ATMTDP1ALDH1A1CA1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458197-A2 Use of N-haloamides as photoinitiators for free-radical polymerizations MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1991-11-27 EP claimed
EP-0458197-A2 Use of N-haloamides as photoinitiators for free-radical polymerizations MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1991-11-27 EP disclosed