Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439505 | 0.88 | SMN1; SMN2 (0.42) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL3133484 | 0.73 | SMN1; SMN2 (0.50) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL1748164 | 0.72 | SMN1; SMN2 (0.53) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL9744120 | 0.72 | ALOX5 (0.55) | SMN1; SMN2NPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL9744062 | 0.71 | F10 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL9744944 | 0.70 | LOXL2 (0.42) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL9748037 | 0.70 | TMEM97 (0.38) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL9439692 | 0.69 | ALDH1A1 (0.56) | SMN1; SMN2HTTALDH1A1LMNAMAPT | |
| SCHEMBL32679815 | 0.67 | NPC1 (0.48) | SMN1; SMN2HTTALDH1A1LMNAMAPT | |
| SCHEMBL25338846 | 0.67 | ALDH1A1 (0.54) | SMN1; SMN2HTTALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |