Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol Diacetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GALR3 | O60755 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol Diacetate SCHEMBL106743 | 0.92 | TDP1 (0.40) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL2466143 | 0.92 | TDP1 (0.42) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL107287 | 0.92 | TDP1 (0.42) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL107443 | 0.91 | TDP1 (0.41) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL107109 | 0.89 | TDP1 (0.40) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL106590 | 0.88 | TDP1 (0.39) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL5485959 | 0.85 | TDP1 (0.37) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL7923868 | 0.85 | TDP1 (0.37) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL23116479 | 0.84 | TDP1 (0.34) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| Propylene Glycol Diacetate SCHEMBL4196506 | 0.84 | ALDH1A1 (0.35) | TDP1TSHRCHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418870-A2 | Radiation sensitive polymer composition | TORAY INDUSTRIES, INC. (JP) | 1991-03-27 | — | — | EP | disclosed |