Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607322 | 0.94 | MAOA (0.43) | MAOAMAOBATMTDP1MAPT | |
| SCHEMBL49774 | 0.89 | ALOX15 (0.43) | ATMTDP1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL53274 | 0.86 | MAPT (0.36) | MAOAMAOBATMTDP1MAPT | |
| SCHEMBL18180026 | 0.85 | MAOA (0.37) | MAOAMAOBATMTDP1MAPT | |
| SCHEMBL12583807 | 0.84 | MAOA (0.45) | MAOAMAOBATMTDP1MAPT | |
| SCHEMBL10416153 | 0.84 | MAOB (0.45) | MAOAMAOBATMTDP1MAPT | |
| SCHEMBL15699449 | 0.84 | SRD5A2 (0.41) | MAOAMAOBLMNAPOLB | |
| SCHEMBL23054908 | 0.83 | BRD4 (0.46) | MAPTALDH1A1POLB | |
| SCHEMBL11887460 | 0.82 | MAOA (0.41) | MAOAMAOBATMTDP1MAPT | |
| SCHEMBL42261 | 0.82 | MAOA (0.53) | MAOAMAOBATMTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424041-A2 | Membranes obtained from copolymers of polyimides and aliphatic polyesters. | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-04-24 | — | — | EP | claimed |