Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849881 | 0.86 | GAA (0.55) | GAAMEN1KMT2ATSHRLMNA | |
| SCHEMBL9849573 | 0.86 | KMT2A (0.49) | QPCTMEN1KMT2ATSHRLMNA | |
| SCHEMBL9849295 | 0.77 | TSHR (0.55) | GAATSHRMAPK1ALDH1A1GSK3A | |
| SCHEMBL9849636 | 0.73 | TSHR (0.54) | GAATSHRMAPK1ALDH1A1GSK3A | |
| SCHEMBL9849334 | 0.71 | KDM4E (0.53) | QPCTGAAMEN1KMT2ATSHR | |
| SCHEMBL28041370 | 0.71 | PARP1 (0.48) | GAAMEN1KMT2ATSHRLMNA | |
| SCHEMBL9849578 | 0.68 | ALDH1A1 (0.61) | QPCTGAAMEN1KMT2ATSHR | |
| SCHEMBL9849597 | 0.67 | SOD1 (0.48) | QPCTTSHRALDH1A1KDM4EPOLB | |
| SCHEMBL11247886 | 0.67 | POLB (0.68) | QPCTGAAKMT2ALMNAKDM4E | |
| SCHEMBL9849395 | 0.67 | CYP19A1 (0.52) | GAATSHRMAPK1ALDH1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |