Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849331 | 0.86 | QPCT (0.45) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL9849295 | 0.83 | TSHR (0.55) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL9849636 | 0.80 | TSHR (0.54) | TSHRALDH1A1MAPK1 | |
| SCHEMBL9849547 | 0.73 | QPCT (0.50) | KMT2AMEN1TSHRALDH1A1MAPK1 | |
| SCHEMBL9849881 | 0.72 | GAA (0.55) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL20701924 | 0.72 | PRKCI (0.53) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL9849578 | 0.71 | ALDH1A1 (0.61) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL9849597 | 0.68 | SOD1 (0.48) | TSHRALDH1A1KDM4EPOLBQPCT | |
| SCHEMBL9849395 | 0.68 | CYP19A1 (0.52) | TSHRALDH1A1MAPK1ALOX15POLB | |
| SCHEMBL28803051 | 0.68 | CYP19A1 (0.49) | KMT2AMEN1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |