Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849368 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ARAB9ANPC1KDM1A | |
| SCHEMBL9615471 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2ARAB9ANPC1POLB | |
| SCHEMBL9849304 | 0.75 | RXFP1 (0.49) | SMN1; SMN2POLBLMNA | |
| SCHEMBL11660474 | 0.74 | IDO1 (0.54) | KMT2ARAB9ANPC1P2RX7POLB | |
| SCHEMBL9849527 | 0.70 | ALDH1A1 (0.44) | KMT2ARAB9ANPC1P2RX7KDM1A | |
| SCHEMBL11660980 | 0.69 | HPGD (0.54) | SMN1; SMN2KMT2ARAB9ANPC1P2RX7 | |
| SCHEMBL31582251 | 0.68 | LMNA (0.56) | SMN1; SMN2KMT2ARAB9ANPC1POLB | |
| SCHEMBL11661149 | 0.68 | ALDH1A1 (0.60) | SMN1; SMN2KMT2ARAB9ANPC1POLB | |
| SCHEMBL25464181 | 0.67 | GRM7 (0.73) | KMT2ARAB9AKDM1AMEN1LMNA | |
| SCHEMBL8225263 | 0.67 | GRM7 (0.73) | KMT2ARAB9AKDM1AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454459-A2 | Sulfonylalkanoic acid amide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-10-30 | — | — | EP | disclosed |