Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901691 | 0.83 | ALDH1A1 (0.48) | CYP3A4TRPA1ALDH1A1ALOX15CHRM1 | |
| SCHEMBL9849381 | 0.81 | CYP3A4 (0.55) | CYP3A4MAPK1TRPA1ALDH1A1ALOX15 | |
| SCHEMBL5677638 | 0.79 | CYP3A4 (0.46) | CYP3A4MAPK1TRPA1ALDH1A1ALOX15 | |
| SCHEMBL1157142 | 0.79 | CYP3A4 (0.46) | CYP3A4MAPK1TRPA1ALDH1A1ALOX15 | |
| SCHEMBL3684343 | 0.79 | TRPA1 (0.44) | CYP3A4MAPK1TRPA1ALDH1A1ALOX15 | |
| SCHEMBL6182858 | 0.77 | MAPK1 (0.55) | CYP3A4MAPK1ALDH1A1ALOX15TSHR | |
| SCHEMBL3945285 | 0.75 | CYP3A4 (0.39) | CYP3A4MAPK1TRPA1ALDH1A1ALOX15 | |
| SCHEMBL14832636 | 0.75 | ALDH1A1 (0.40) | CYP3A4TRPA1ALDH1A1ALOX15CHRM1 | |
| SCHEMBL94507 | 0.75 | CYP3A4 (0.43) | CYP3A4MAPK1TRPA1ALDH1A1ALOX15 | |
| SCHEMBL12886366 | 0.75 | ALDH1A1 (0.40) | CYP3A4TRPA1ALDH1A1ALOX15CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104752763-B | Novel lithium ion electrolyte solution additive system | 中国科学院宁波材料技术与工程研究所 | 2017-04-12 | — | — | CN | claimed |
| CN-107922741-A | Resin combination | 日本瑞翁株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-104752763-B | Novel lithium ion electrolyte solution additive system | 中国科学院宁波材料技术与工程研究所 | 2017-04-12 | — | — | CN | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-0387554-A2 | Liquid epoxy polymer composition and use thereof | International Business Machines Corporation (US) | 1990-09-19 | — | — | EP | disclosed |
| EP-0375980-A2 | Epoxy composition of increased thermal conductivity and use thereof | International Business Machines Corporation (US) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CYP3A4 177/4885MAPK1 4726/4885TRPA1 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.