Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SOD1 | P00441 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849299 | 0.84 | ALDH1A1 (0.65) | QPCTKMT2AMEN1ALDH1A1SOD1 | |
| SCHEMBL9849642 | 0.81 | ALDH1A1 (0.61) | QPCTKMT2AMEN1ALDH1A1SOD1 | |
| SCHEMBL5943507 | 0.78 | MCHR1 (0.62) | MCHR1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3627950 | 0.78 | QPCT (0.54) | QPCTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9849578 | 0.77 | ALDH1A1 (0.61) | QPCTKMT2AMEN1ALDH1A1SOD1 | |
| SCHEMBL77764 | 0.75 | QPCT (1.00) | QPCTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9849547 | 0.74 | QPCT (0.50) | QPCTKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL3633355 | 0.74 | LMNA (0.53) | QPCTALDH1A1SOD1MAPTNAMPT | |
| SCHEMBL3629884 | 0.73 | NAMPT (0.56) | QPCTKMT2AMEN1SOD1MAPT | |
| SCHEMBL9849889 | 0.73 | GSK3A (0.64) | QPCTKMT2AMEN1ALDH1A1SOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |