Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849709 | 0.99 | LMNA (0.39) | KDM4ELMNATSHRUSP2ALDH1A1 | |
| SCHEMBL9849893 | 0.96 | DAO (0.39) | KDM4ELMNATSHRUSP2ALDH1A1 | |
| SCHEMBL9849875 | 0.91 | DAO (0.41) | KDM4ELMNATSHRUSP2ALDH1A1 | |
| SCHEMBL1604772 | 0.80 | CYP4A11 (0.54) | KDM4EALDH1A1DAOCTPS1NPSR1 | |
| SCHEMBL9849871 | 0.79 | CYP4A11 (0.53) | ALDH1A1DAOCTPS1NPSR1MAPT | |
| SCHEMBL9849635 | 0.79 | CYP4A11 (0.53) | KDM4ETSHRALDH1A1DAOCTPS1 | |
| SCHEMBL28342951 | 0.77 | DAO (0.44) | KDM4ELMNATSHRALDH1A1ALOX15 | |
| SCHEMBL9849816 | 0.76 | LMNA (0.40) | KDM4ELMNATSHRUSP2ALDH1A1 | |
| SCHEMBL12468480 | 0.76 | DAO (0.46) | TSHRDAONPSR1MAPTCYP4A11 | |
| SCHEMBL9849790 | 0.76 | CTPS1 (0.36) | KDM4ELMNATSHRUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415510-A2 | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4920125-A | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-04-24 | — | — | US | disclosed |