Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 5/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558971 | 0.78 | ANPEP (0.46) | CAPN1CTSBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9558477 | 0.76 | PLA2G2A (0.45) | CAPN1CTSBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5279103 | 0.75 | ANPEP (0.48) | CYP3A4CYP2C9CYP2C19ANPEPPLA2G10 | |
| SCHEMBL9558884 | 0.73 | PLA2G2A (0.49) | ANPEPPLA2G10PLA2G2ABACE1 | |
| SCHEMBL5950912 | 0.69 | PPARG (0.51) | CAPN1CTSBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5950916 | 0.69 | PPARG (0.51) | CAPN1CTSBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11863901 | 0.69 | KIF11 (0.58) | CYP3A4CYP2C9CYP2C19ANPEPGRIK1 | |
| SCHEMBL11863917 | 0.69 | KIF11 (0.58) | CYP3A4CYP2C9CYP2C19ANPEPGRIK1 | |
| SCHEMBL9644585 | 0.69 | GRIK1 (0.45) | CAPN1CTSBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9558499 | 0.68 | CASP1 (0.41) | ANPEPPLA2G10ALDH1A1LMNAPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433064-A1 | Naphthylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1991-06-19 | — | — | EP | disclosed |